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KMID : 0032220090210010053
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Annals of Dermatology
2009 Volume.21 No. 1 p.53 ~ p.55
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A Case of Isolated Plexiform Neurofibroma in a Patient with Myasthenia Gravis
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Back Seung-Ju
Seo Young-Joon
Lee Jeung-Hoon
Park Jang-Kyu
Lee Young
Kim Dae-Hun
Kim Na-Ri
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Abstract
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We report a case of an isolated plexiform neurofibroma occurring in a patient with myasthenia gravis. A 48-year-old man presented with asymptomatic skin-colored nodules on the tip of his 4th finger. Microscopically, a plexiform neurofibroma was identified located in the dermis that appeared to originate from small superficial nerves. He had a 20-year history of treated myasthenia gravis; otherwise, his personal and family histories were unremarkable. Given that myasthenia gravis is a disorder of the peripheral nerves, plexiform neurofibromas could be associated with myasthenia gravis. However, the development of an isolated plexiform neurofibroma in a case of myasthenia gravis has not yet been reported. The occurrence of a neurofibromas in a patient with myasthenia gravis suggests a link in the pathogenesis of these two diseases.
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KEYWORD
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isolated, Myasthenia gravis, Plexiform neurofibroma
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